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Nexium is a medicine to treat heartburn and other illnesses associated with gastroesophageal reflux disease. It is marketed in France under the name Inexium and is manufactured in the United Kingdom by the AstraZeneca laboratory.

About Nexium

Nexium (Inexium) granules and tablets contain a proton pump inhibitor; esomeprazole. This active substance helps reduce the level of acid produced by the stomach. Thus, the drug Inexium relieves the symptoms caused by gastroesophageal reflux disease, such as heartburn and acid reflux. The tablets are swallowed with water while the granules dissolve directly in water, before swallowing them.

  1. Available as granules and tablets
  2. Effective against heartburn
  3. Frequently prescribed treatment

Heartburn is one of the most common symptoms experienced by patients with gastroesophageal reflux disease (GERD). More precisely, this reflux can be described as the unpleasant sensation felt in the chest and resulting from the rise towards the esophagus of the natural acids found in the stomach. This same acid can also reach the throat causing a sour, burning sensation also known as acid reflux. Heart disease can also occasionally cause pain similar to heartburn.

(Occasionally, heartburn in the chest can also be a sign of heart disease. It is therefore important to see a doctor as soon as possible if you are experiencing these symptoms for the first time or if they are more painful. than usual.)

Gastroesophageal reflux disease results from the relaxation of the ring of muscles between the esophagus and the stomach and causing acid to rise up in the throat. A number of circumstances favor the onset of heartburn, such as smoking, excessive consumption of fat, alcohol or coffee, and being overweight. These gastric symptoms can also be caused by stress, pregnancy or if your family circle is also concerned.

People with heartburn usually need to make some lifestyle changes to reduce the severity of symptoms. Thus, it is recommended to follow a balanced diet, exercise regularly, stop smoking or even sleep with your head up. However, if symptoms persist despite these preventative measures and over-the-counter treatments are not effective, your doctor may decide to prescribe prescription medication.

Inexium contains esomeprazole as an active agent, which belongs to the drug category of proton pump inhibitors. The proton pumps are positioned on the lining of the stomach and this is what allows the production of digestive acid. Esomeprazole reduces the amount of acid produced by the body and therefore prevents gastroesophageal reflux disease.

Inexium (Nexium) is also prescribed to treat diseases related to the production of acid in the stomach, including the prevention and treatment of ulcers for patients who take nonsteroidal anti-inflammatory drugs (NSAIDs) for long term and patients with ulcers in the digestive tract and caused by the bacterium Helicobacter pylori.

To refill your heartburn treatment prescription, take a few minutes of your time to complete our medical form. Once your order has been validated by one of our doctors, it will be prepared by our UK based pharmacy or one of our partners located in Europe and delivered within 24 hours.

Usage tips

Before starting your medication, be sure to read your patient information leaflet and follow the medical instructions given by your doctor. These precautions will help you reduce the risk of side effects and optimize the performance of Inexium.

  1. Take the medication as prescribed
  2. The dosage will be determined by the doctor, depending on the disease to be treated and the severity of the symptoms.

Nexium granules

  1. Each sachet of Inexium granules (Nexium) contains 10 mg of esomeprazole
  2. Empty the contents of the sachet into a glass of water. Each sachet should be diluted in 15 ml of water (three teaspoons), so two sachets require 30 ml of water and so on
  3. Mix the water and wait a few moments for the mixture to thicken
  4. Stir the mixture again and drink it. If any pellets remain, add a little more water and swallow the rest
  5. Do not wait more than thirty minutes to drink the mixture

Nexium tablets

  1. Swallow it or the tablets with a glass of water
  2. You can take your tablet at any time of the day, with or without food.
  3. If you have difficulty swallowing your tablets, you can also place them in water and mix them. To do this, place your tablets in a glass of water and mix, without crushing them. Drink the mixture within thirty minutes

For both versions:

  1. If you forget your dose of Inexium, swallow it as soon as you remember, unless it is almost time for your next dose. In this case, do not take the missed tablet and continue your treatment as planned.
  2. Never swallow a double dose to make up for a forgotten

These indications are provided for information only. For a complete list of instructions, see the Nexium (Inexium) Patient Information Leaflet.

Side effects

ide effects will not affect all patients. Nevertheless, it is important to know the potential list that the drug may generate, in order to react accordingly if you are concerned. Seek medical attention immediately if you develop an allergic reaction to the medicine, including swelling of the face, difficulty swallowing or breathing, wheezing or fainting.

Common (1 in 10 people or less):

Vomiting or nausea, gas, stomach pain, constipation, diarrhea or headache.

Uncommon (1 in 100 people or less):

Drowsiness or insomnia, change in liver function, dry mouth, dizziness or vertigo, hives, paresthesia (tingling), swelling of the feet or ankles. There is also a risk of fracture of the hip, waist or spine if the treatment is used for the long term.

Exceptional (1 in 1,000 people or less):

Blood disorders, blurred vision, yeast infection, hair loss, jaundice, hepatitis, muscle or joint pain, anxiety or depression, sweating, changes in taste buds or shortness of breath.

Very exceptional (1 in 10,000 people or less):

Hallucinations, feeling angry or hostile, change in blood count, acute liver or kidney disease, blistering or peeling of the skin, severe itching.

This list is not exhaustive. Please consult the Nexium (Inexium) medical leaflet for a full list of side effects this treatment may cause.

Drugs interactions

When completing the medical questionnaire, please be sure to provide all of the medications you are currently taking. Do not take Inexium with nelfinavir, prescribed for HIV treatment.

If you are taking any of the following treatments, please be especially careful: atazanavir; diazepam; digoxin; phenytoin, clopidogrel; rifampicin; tacrolimus; the antidepressant imipramine, citalopram, or clomipramine; erlotinib or methotrexate (both used to treat cancer); the antifungal drug itraconazole, ketoconazole or voriconazole; cisapride; cilostazol; warfarin or coumarin; natural products containing extracts of St. John’s Wort.

Precautions for use

If you are allergic to any of the ingredients in Inexium or other proton pump inhibitors such as pantoprazole or lansoprazole, do not take this medicine. If you suffer from kidney or liver disease, have ever developed skin irritation or inflammation while using this medicine or similar treatment, it is important to tell your doctor.

Pregnancy and breast feeding

If you are pregnant or trying to get pregnant, you will need to check with your doctor that you can take this medical treatment.

If you are breast-feeding, do not take Nexium.

Driving and using machines

If you develop side effects such as dizziness or sight problems, do not drive or use machines.

Sucrose and glucoce intolerance

If you are intolerant to certain types of sugar, please tell your doctor. Nexium contains sucrose and glucose. 


Can I drink alcohol?

Nexium is not expected to interact with alcohol. However, consuming too much alcoholic beverages can make your heartburn worse.

Can I take Inexium if I am driving?

Yes, unless you develop side effects that make driving unsafe. If you suffer from side effects such as dizziness, drowsiness, do not drive and contact your doctor.

Can I take Inexium if I am pregnant?

If you are pregnant, or think you might be, first talk to your doctor before taking this treatment. If you are breast-feeding, taking Inexium is not recommended because there are doubts about the transmission of the active agent through breast milk.

How to store the medicine Inexium?

Store it in a room at room temperature and do not use it after the expiration date.

Am I allergic to the ingredients in Inexium?

Nexium (Inexium) tablets contain the following ingredients: esomeprazole, glycerol monostearate 40-55, hyprolose, hypromellose, iron oxide (20 mg reddish brown, yellow, 40 mg reddish brown) (E172), synthetic paraffin, stearate of magnesium, Copolymer of methacrylic acid and acrylate (1: 1) dispersion 30%, microcrystalline cellulose, macrogol, polysorbate 80, crospovidone, sodium stearyl fumarate, microbead sugar (sucrose and corn starch), talc, dioxide titanium (E171), and triethyl citrate.

The granules consist of: esomeprazole, glycerol monostearate 40-55, magnesium stearate, hydroxypropyl cellulose, methacrylic acid – ethyl acrylate copolymer (1: 1) 30% dispersion, hypromellose, microbead sugar, talc, polysorbate 80, triethyl citrate, anhydrous citric acid, hydroxypropylcellulose, iron oxide yellow, crospovidone, glucose and xanthan gum.

If you are allergic to any of these ingredients, the prescription of Inexium (Nexium) is contraindicated for you.

Is Innexium available without a prescription?

No, you can buy Inexium only through the issuance of a medical prescription.

Is this the right medicine for me?

If this is the first time you develop heartburn symptoms or think your heartburn has worsened, see your doctor as soon as possible. They can carry out a medical examination and prescribe appropriate treatment.

To renew your Inexium prescription, complete our medical form now, your answers will be checked by one of our doctors. If your order is validated, the package will be prepared by our pharmacy and delivered within 24 hours.

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