Avanafil is a drug used to treat erectile dysfunction. You can buy Avanafil online simply and safely using our confidential pharmacy service.
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What exactly is Avanafil?
Avanafil, which is the main ingredient of Stendra Spedra, is an ED treatment drug that is more effective than the existing ED drugs Viagra (sildenafil), Levitra (vardenafil), and Cialis (tadalafil). It is also less susceptible to food and alcohol.
Originally developed by Mitsubishi Tanabe Pharma, a pharmaceutical company in Japan, In February 2001, the pharmaceutical company Vivus, located in California, USA, acquired the right to manufacture and sell, excluding Japan and Asia. “Stendra” has been sold.
Dosage and Administration of Avanafil (Stendra)
Stendra, the main ingredient of Avanafil, is available in 50mg, 100mg, and 200mg tablets, with a daily dose of up to 200mg of Avanafil. Avanafil is characterized by its immediate effect, but since it is a mild ED treatment, we recommend taking 200 mg.
Avanafil’s effect and duration of effect
Avanafil’s Mechanism of Action
Avanafil is a PDE-5 inhibitor like Viagra, Levitra, and Cialis. There is an enzyme called cGMP (cyclic GMP) that maintains the erection state by promoting the dilation of blood vessels by receiving sexual excitement and sexual stimulation and allowing blood to flow into the corpus cavernosum of the penis. PDE-5 (phosphodiesterase type 5) breaks down cGMP, making it impossible to maintain an erection. Avanafil is an ED drug that inhibits the action of PDE5, relatively increasing the proportion of cGMP in the body and temporarily promoting an erection.
Features of Avanafil
One of Avanafil’s greatest strengths is its rapid onset of action. Viagra takes about 30 minutes to an hour to take effect, while Avanafil takes about 15 minutes, although there are individual differences. In addition, one of its features is that it is an ED drug that is not easily affected by food. The duration of effect lasts approximately 6-8 hours.
How and when to take Avanafil
The dosage is basically the same as Viagra.
Avanafil has a fast-acting effect that takes effect in 15 minutes, but if you want to have room for sexual activity, take it with water or plain hot water (lukewarm water) about 20 to 30 minutes before. Please note that if you take this medicine with fatty milk, etc., it will form a film on the stomach wall and interfere with digestion and absorption. Wait 24 hours before taking the next dose. Like Cialis, Avanafil is less affected by food, but both Avanafil and Cialis are less effective immediately after meals, so all ED drugs should be taken on an empty stomach.
Avanafil side effects
The symptoms are transient and similar to those experienced after drinking alcohol.
Avanafil is known to have few side effects. However, like other ED drugs, it dilates blood vessels and improves blood flow, so side effects similar to those of Viagra, Levitra, and Cialis have been confirmed. The main side effects include “hot flashes of the face,” “bloodshot eyes”, “stuffy nose”, “dizziness”, “palpitations” and “headache”. Such symptoms are likely to occur due to the sudden promotion of blood circulation, but they are often mild symptoms. Some say they don’t care at all. Therefore, there is no problem with thinking that it is a sign that the medicine has started to work. In rare cases, symptoms of temporary visual disturbance may occur, such as “dazzling” and “colors appearing different than usual.”
Most of the side effects disappear when the action of avanafil disappears, so there is no problem. However, if symptoms persist for a long period of time, please consult your doctor immediately. Avanafil, like other ED drugs, has no known serious side effects. Please do not worry too much and take it safely.
Please note that those who apply for the following items cannot take Avanafil.
Avanafil has the most contraindications for co-administration compared to other ED drugs. Nitrates, nitroglycerin, amiodarone hydrochloride, etc. are basically the same as other ED drugs and may cause blood pressure to drop too much. Concomitant use of CYP3A4 inhibitors with Viagra and Cialis is contraindicated, as are some antifungal drugs with which Levitra is contraindicated, and HIV protease inhibitors, which are HIV treatment drugs, are also contraindicated.
In addition, “persons with chronic diseases such as arrhythmia, angina pectoris, and heart failure”, “persons with low blood pressure or uncontrolled hypertension”, “persons with severe liver dysfunction”, and “severe renal function” Persons with disabilities, people undergoing dialysis, people who have undergone heart surgery or had a cerebral infarction within the past 6 months, people with multiple myeloma, leukemia, sickle cell anemia, etc. Avanafil should not be used by people who have “cell problems,” “Penis deformity,” or “retinitis pigmentosa (night blindness, narrowing of the visual field).” When taking ED drugs, be sure to visit a medical institution, bring a medicine notebook that shows your chronic diseases and the drugs you are using, and take them correctly under the guidance of your doctor.