Amoxicillin is one of the penicillin antibiotics and can be used for antibiotic treatment. It is mainly used to fight bacterial infections.
How does amoxicillin work?
Amoxicillin is an antibiotic treatment and is based on the active ingredient of the same name. It is one of the penicillin antibiotics. When fighting bacterial infections, amoxicillin is a popular choice. An antibiotic works by weakening the bacterium’s cell wall. In this way, an antibiotic can kill the bacteria. If the bacteria die, the bacterial infection should subside. The bacteria finds the means by which it gets from the digestive tract into the bloodstream and thus into the tissue where the bacteria usually reside. The antibiotic also reaches the urine and can kill any bacteria there. Amoxicillin scores with the fact that it is suitable for pregnant women and children.
How do you get amoxicillin?
If there are symptoms that indicate a bacterial infection, you should go to your doctor. They can confirm the bacterial infection and write a prescription. With this prescription, the drug can be picked up at any pharmacy. The faster amoxicillin can start its work, the faster the bacterial infection is history.
Where is amoxicillin used?
Doctors use prescription antibiotic treatments to fight bacterial infections. There are different types, such as (general) respiratory infections, cystitis, bronchitis, chlamydia, meningitis, pneumonia, otitis media or sinus infections. Because amoxicillin can be used against so many types of bacteria, it is also called a broad spectrum antibiotic. A bacterial infection includes side symptoms such as fever, illness-related malaise and pain. Once the amoxicillin starts working, these symptoms will quickly subside.
Amoxicillin is used against these bacterial infections.
Respiratory diseases such as:
- Sore throat
- Lung infection
- Otitis media
- Sinus infection
Here are the other areas of application:
- Bladder infections
- Chlamydia (a sexually transmitted disease)
- Skin infections
- Infections of the gastrointestinal tract
- Lyme disease (can be transmitted through a tick bite)
When does amoxicillin not work?
Amoxicillin is an antibiotic, which means that the agent only works if the infection is due to a bacterium. If the cause of the disease is a virus, an antibiotic cannot help. Therefore, a doctor will not prescribe antibiotics for a viral infection. Viral diseases are for example: childhood diseases such as measles, rubella or chickenpox, liver inflammation, hepatitis, infections such as HIV / AIDS and also some gastrointestinal diseases. However, so that there are not more and more bacteria for which an antibiotic no longer works, the prescribing of antibiotics by doctors is decreasing somewhat and alternatives are used whenever possible.
How is amoxicillin used correctly?
The remedy is available in different forms, such as effervescent tablets or capsules. The effervescent tablets are perfect for people who cannot swallow tablets, for example children, or patients with motor or mental disabilities. The effervescent tablets are dissolved in half a glass of water, stirred well and drink immediately after dissolving.
If you have no problem swallowing tablets, your doctor will prescribe capsules. The capsules are swallowed whole with sufficient water. You are not dependent on eating at the same time.
A little tip for swallowing tablets:
Many people put their heads back when they want to swallow pills. However, this worsens the chances of being able to swallow the tablet well. Because by overstretching the head backwards, the diameter of the esophagus narrows. It is better to put the tablet in your mouth, take a long sip of water and bend your head forward. The tablet slips through as if by itself.
What to do if you forget to take a capsule of amoxicillin?
It is important to keep antibiotic treatment through to the end. If you stop taking the antibiotic early, it is possible that not all bacteria have been killed yet. The result would be that the bacteria recover, multiply again and the infection flares up again. There is always the danger that the bacteria are capable of learning and can better withstand the antibiotic the next time they try. Nevertheless, it can always happen that a tablet is forgotten. Basically, the intake should be made up as soon as possible. If you only notice that you have forgotten when the next dose is just around the corner, you do not take the missing tablet right before the next dose, but attach the tablet to the end of the cure. If the cure had ended on Monday morning, for example, the missing tablet would be swallowed on Monday evening.
Amoxicillin and the side effects
In any case, you must follow the doctor’s instructions and read the package insert. Amoxicillin can be taken during pregnancy and breastfeeding, but only after consultation with the (gynecologist) doctor.
Known side effects are:
- an allergic reaction, such as rash or urticaria
- anaphylactic shock
- an increase in liver enzymes
- Drug fever
- Changes in the blood count, such as eosinophilia, liver dysfunction, leukopenia, neutropenia or thrombocytopenia;
- Signs of fatigue
- Taste disorders
- Skin rash
- Liver dysfunction
- Gastrointestinal complaints
- pseudomembranous colitis
- Sleep disorders
- Inflammation of the mucous membranes
- Discoloration of teeth
- mild confusion
If you have a known allergy to penicillin, amoxicillin should not be used.
The side effects occur in 1 in 1,000 people.
What to do if side effects are suspected after taking?
Amoxicillin is a doctor-prescribed drug. So that it can develop its full effect and the infection can heal completely, the cure must be taken in full. If side effects occur, it is not advisable to continue taking it. For one thing, the patient does not want to take drugs that cause negative consequences. On the other hand, the side effects can impair the effectiveness of the drug. Therefore, you should consult with the doctor who prescribed the drug to switch to a drug that helps against the infection and protects the patient.
The story of amoxicillin
Amoxicillin was approved for the treatment of infections in 1981. It is a broad spectrum antibiotic, which means it is able to kill various bacteria and belongs to the aminopenicillin group, which means it belongs to the group of active substances called ß-lactam antibiotics. The drug can be used orally or parenterally. Oral means that you ingest it with your mouth through the digestive tract, for example as a capsule or an effervescent tablet. Parenteral means bypassing the digestive tract, which means that a drug is injected, i.e. injected. It is a finished medicinal product that is also commercially available under other names.
What types of bacteria does amoxicillin work against?
Amoxicillin is used to treat infections of the respiratory tract, the biliary tract, the lower urinary tract, the skin (for example after animal bites), the gastrointestinal tract, the middle ear or rhinosinusitis. The bacteria responsible for such infections are gram-positive and some gram-negative bacteria, such as enterobacteria. The great advantage of amoxicillin is less damaging to the flora of the intestine than ampicillin and because it is acid-stable, it can be taken orally. But it can also be injected.
What speaks against taking amoxicillin?
Amoxicillin should not be used if an allergy to penicillin is known. The same applies if there is hypersensitivity to one of the ingredients. This hypersensitivity can also exist to carrier substances.
Who shouldn’t take amoxicillin?
The drug should not be used in children who have not yet reached the age of six.
Can amoxicillin be used during pregnancy and breastfeeding?
Here you should consult your doctor. There are several factors that can influence the decision whether or not to use this drug during pregnancy.
Even when breastfeeding, the doctor should be asked whether the drug can be taken or whether it is necessary to stop breastfeeding.
The plasma half-life averages around 60 minutes in healthy kidneys. Amoxicillin is for the most part excreted via the kidneys, a small proportion in the bile.
How well is amoxicillin absorbed?
Amoxicillin can be taken regardless of timely food intake. If the agent is taken orally, about 80 percent of it is absorbed. Much of the drug is eliminated through the kidneys without any change. The 20 percent plasma protein binding is so low that it can be neglected.
What is plasma protein binding?
With plasma protein binding, called PPB for short, is the reversible binding of substances such as medicinal substances to the proteins in the blood plasma
Plasma protein binding, or PPB for short, refers to the reversible binding of substances – mostly medicinal products – to proteins in the blood plasma. The part of the drug that attaches to a protein usually no longer works. In addition, the breakdown of the drug is slowed down by the binding, in other words, the half-life of the drug becomes longer than usual. This is particularly important when it comes to interaction with other drugs.